K. Warpeha, T. Park, A. Chee, H. An, C-T. Che, J. Nguyen, T. Ozbolt
University of Illinois Chicago, Illinois, United States
Keywords: antiinflammatories, encapsulation technology, mobile warrior nutraceutical, living sensor, extractsOur collaborative effort has resulted in materials that can be made into products to support warfighters and veterans. Specific growth regimes of cruciferous plants lead to output of chemicals with high proportions of defensive atypical ‘alternative’ chemicals including polyphenols and polyamines that may address multiple underlying features of inflammation. Extracts prevent inflammatory pain in a mouse model, reduce inflammation responses in a rabbit spine injury/surgery model, and promote a neuro-regenerative environment, detected by established indicators. The products are stable over time and can be concentrated to reduce weight for the carrier. In another capacity, same-origin plant materials can be processed into encapsulations can detect chemical signatures, with potential for use in detection of EDPs. Many EDPs are persistent and utilize hidden means of survival in ecosystems, where unauthorized actors can take advantage of edge effect, dispersal, dormancy and potential for alteration, which contribute to weaponized organisms. Detection of chemicals of pathogens/toxins creates a chemical change in the plant product microcell that can be detected within seconds to minutes. We are seeking funding to optimize delivery options, health outcomes and to explore detection, analysis and transmission hardware design. 1 Patent and Patents applied for; non-published data.